PUBLICATIONS

2024:

2023:

• 2023 - Cummings, J.L., Osse, A.M.L., Kinney, J.W., Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification. Drugs. 2023

• 2023 - Cummings, J.L., Osse, A.M.L., Kinney, J.W., Geroscience and Alzheimer’s Disease Drug Development. The Journal of Prevention of Alzheimer’s Disease. 2023

• 2023 - Cummings, J.L., Osse, A.M.L., Cammann, D., Powell, J., Chen, J., Anti-Amyloid Monoclonal Antibodies for the Treatment of Alzheimer’s Disease. BioDrugs. 2023

• 2023 - Yang, Z., Sreenivasan, K.R., Strom, E.N., Osse, A.M.L., Pasia, L.G., Cosme, C.G., Mugosa, M.N., Chevalier, E.L., Ritter, A., Miller, J.B., Cordes, D., Cummings, J., Kinney, J.W. Clinical and biological relevance of glial fibrillary acidic protein in Alzheimer’s disease. Alzheimer’s Research & Therapy. 2023

• 2023 - Amanda M. Leisgang Osse, Ravi S. Pandey, Ryan A. Wirt, Andrew A. Ortiz, Arnold Salazar, Michael Kimmich, Erin N. Toledano Strom, Adrian Oblak, Bruce Lamb, James M. Hyman, Gregory W. Carter, Jefferson Kinney. Reduction in GABAB on glia induce Alzheimer’s disease related changes.

2022:

• 2022 - Emily Hensleigh, Andrew S. Murtishaw, Michael D. Treat, Chelcie F. Heaney, Monica M. Bolton, Jonathan J. Sabbagh, Kirsten N. Calvin, Jefferson W. Kinney, and Frank van Breukelen. Torpor Does Not Influence Spatial Memory in Hibernating Golden-Mantled Ground Squirrels (Spermophilus [Callospermophilus] lateralis)

• 2022 - Jeffrey Cummings & Jefferson Kinney. Biomarkers for Alzheimer’s Disease: Context of Use, Qualification, and Roadmap for Clinical Implementation

• 2022 - Zhengshi Yang, Filippo Cieri, Jefferson Kinney, Jeffrey Cummings, Dietmar Cordes, Jessica Caldwell. Brain Functional Topology Differs by Sex in Cognitively Normal Older Adults

• 2022 - Jeffrey Cummings, Jefferson Kinney, Howard Fillit, Amanda-Leisgang Osee. Alzheimer's Disease Drug Development Research and Development Ecosystem

• 2022 - Jeffrey Cummings, Andrew Ortiz, Janelle Castellino, Jefferson Kinney. Diabetes: Risk factor and translational therapeutic implications for Alzheimer's disease

• 2022 - Marwan Noel Sabbagh, Aaron Ritter, Jeffrey L. Cummings, Dylan Wint, Boris Decourt, Christina G Wong, Jessica ZK Caldwell, Jefferson W Kinney, Lucille Carriere, Dietmar Cordes, Nadia Fulkerson, Abla Almoraissi, LeeAnn Mandarino, Katurah Hartley, Guogen Shan, Justin B Miller, Samantha E John, Joseph Lombardo. Nevada exploratory Alzheimer’s disease research center: Advancing dementia care in rural communities

2021:

• 2021 - Ryan. A. Wirt, Lauren. A. Crew, Andrew. A. Ortiz, Adam. M. McNeela, Emmanuel Flores, Jefferson. W. Kinney & James M. Hyman. Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease.

• 2021 - A. M. Salazar, A. M. Leisgang, A. A. Ortiz, A. S. Murtishaw, J. W. Kinney (2021). Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer’s Disease.

• 2021 - Arpita Basu, Kenneth Izuora, Nancy M. Betts, Jefferson W. Kinney, Arnold M. Salazar, Jeffrey L. Ebersole, and R.Hal Scofield. Dietary Strawberries Improve Cardiometabolic Risks in Adults with Obesity and Elevated Serum LDL Cholesterol in a Randomized Controlled Crossover Trial

• 2021 - Jessica Z.K. Caldwell, Jefferson Kinney, Aaron Ritter, Arnold M. Salazar, Christina G. Wong, Dietmar Cordes, George M. Slavich. Inflammatory Cytokine Levels Implicated in Alzheimer’s Disease Moderate the Effects of Sex on Verbal Memory Performance

• 2021 - Dawn C. Matthews Aaron Ritter Ronald G. Thomas Randolph D. Andrews Ana S. Lukic Carolyn Revta Jefferson W. Kinney Babak Tousi James B. Leverenz Howard Fillit Kate Zhong Howard H. Feldman Jeffrey Cummings. Rasagiline effects on glucose metabolism, cognition, and tau in Alzheimer's dementia

2020:

• Merrill R. Landers, Kyle N. Johnson, Samantha Johnson, Tyler Ormsby, Danielle C. Salgo, Jessica B. Zorn, James Lyle, Andrew S. Murtishaw, Arnold M. Salazar. Pre-diagnosis physical activity habits are associated with age of diagnosis in Parkinson's disease

2019:

• A. M. Salazar, A. M. Leisgang, Ortiz, A. A., J. W. Kinney (2019). Dementia Insights: What Do Animal Models of Alzheimer’s Disease Tell Us? Practical Neurology. Special invitation by Jeffrey L. Cummings, MD, ScD. 

2018:

• Andrew S.Murtishaw, Chelcie F.Heaney, Monica M.Bolton, Krystal Courtney D.Belmonte, Michael A.Langhardt, Jefferson W.Kinney (2018). Intermittent streptozotocin administration induces behavioral and pathologica features relevant to Alzheimer's disease and vascular dementia.

• Jefferson W. Kinney, Shane M. Bemiller, Andrew S. Murtishaw, Amanda M. Leisgang, Arnold M. Salazar, 

  Bruce T. Lamb (2018). Inflammation as a central mechanism in Alzheimer's disease. 

• Merrill R. Landers; James W. Navalta; Andrew S. Murtishaw; Jefferson W. Kinney; Sarah Pirio Richardson (2018).  A High - Intensity Excerise Boot Camp for Persons With Parkinson Disease: A Phasell, Pragmatic, Randomized Clinical Trial of Feasibility, Safety, Signal of Efficacy, and Disease Mechanisms. 

• Monica M.BoltonChelcie F.HeaneyAndrew S.MurtishawJonathan J.SabbaghChristy M.MagcalasJefferson W.Kinney (2018). Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood. 

2016:

• Cummings JL, Zhong K, Kinney JK, Heaney CF, Moll-Tudla J, Joshi A, Pontecorvo M, Devous M, Tang A, Bena J (2016). Double-blind, placebo-controlled, proof-of-concept trial of bexarotene in moderate Alzheimer's disease. Alzheimer's Research and Therapy. 8:4.

• Heaney CF, Kinney JW (2016). Role of GABAB receptors in learning and memory. Neuroscience and Biobehavioral Reviews. 63:1-28.

• Murtishaw AS, Heaney CF, Bolton MM, Sabbagh JJ, Langhardt MA, Kinney JW (2016). Effect of acute lipopolysaccharide-induced inflammation in intracerebroventricular-streptozotocin injected rats. Neuropharmacology. 101:110-122.

2015:

• Bolton MM, Heaney CF, Murtishaw AS, Sabbagh JJ, Magcalas CM, Kinney JW (2015). Postnatal alterations in GABAB receptor tone produce sensorimotor gating deficits and protein level differences in adulthood. International Journal of Developmental Neuroscience. 41:17-27.

2014:

• Landers MR, Kinney JW, van Breukelen F (2014). Forced exercise before or after induction of 6-OHDA-mediated nigrostriatal insult does not mitigate behavioral asymmetry in a hemiparkinsonian rat model. Brain Research. 1543:263-70.

2013:

• Sabbagh JJ, Kinney JW, Cummings JL (2013). Alzheimer's disease biomarkers in animal models: Closing the translation gap. American Journal of Neurodegegenerative Disease; 2(2):108-120.

• Sabbagh JJ, Murtishaw AS, Bolton MM, Heaney CF, Langhardt M, Kinney JW (2013). Chronic ketamine produces altered distribution of parvalbumin-positive cells in the hippocampus of adult rats. Neuroscience Letters. 550:69-74.

• Sabbagh JJ, Kinney JW, Cummings JL (2013). Alzheimer's disease biomarkers: correspondence between human studies and animal models. Neurobiology of Disease. 56:116-30.

• Landers MR, Kinney JW, Allen DN, van Breukelen F (2013). A comparison of voluntary and forced exercise in protecting against behavioral asymmetry in a juvenile hemiparkinsonian rat model. Behavioural Brain Research. 248:121-8.

• Cummings JL, Banks SJ, Gary RK, Kinney JW, Lombardo JM, Walsh RR, Zhong K (2013). Alzheimer's disease drug development: translational neuroscience strategies. CNS Spectrums. 18(3)128-38.

• Sabbagh JJ, Kinney JW, Cummings JL (2013). Animal systems in the development of treatments for Alzheimer's disease: challenges, methods, and implications. Neurobiology of Aging. 34(1):169-83.

2012:

• Heaney CF, Bolton MM, Murtishaw AS, Sabbagh JJ, Magcalas CM, Kinney JW (2012). Baclofen administration alters fear extinction and GABAergic protein levels. Neurobiology of Learning and Memory. 98(3):261-71.

• Sabbagh JJ, Heaney CF, Bolton MM, Murtishaw AS, Kinney JW (2012). Examination of ketamine-induced deficits in sensorimotor gating and spatial learning. Physiology & Behavior. 107(3):355-63.

• Sabbagh JJ, Heaney CF, Bolton MM, Murtishaw AS, Ure JA, Kinney JW (2012). Administration of donepezil does not rescue galanin-induced spatial learning deficits. International Journal of Neuroscience. 122(12):742-7.

• Bolton MM, Heaney CF, Sabbagh JJ, Murtishaw AS, Magcalas CM, Kinney JW (2012). Deficits in emotional learning and memory in an animal model of schizophrenia. Behavioural Brain Research. 233(1):35-44.

2010:

1. Allen DN, Randall C, Bello D, Armstrong C, Frantom L, Cross C, Kinney J (2010). Are working memory deficits in bipolar disorder markers for psychosis? Neuropsychology. 24(2):244-54.

2009 - start:

• Kinney JW, Sanchez-Alavez M, Barr AM, Criado JR, Crawley JN, Behrens MM, Henriksen SJ, Bartfai T (2009). Impairment of memory consolidation by galanin correlates with in vivo inhibition of both LTP and CREB phosphorylation. Neurobiology of Learning and Memory 92(3):429-38.

• Barr AM, Kinney JW, Hill MN, Lu X, Biros S, Rebeck J Jr, Bartfai T. (2006). A novel, systemically active, selective galanin receptor type-3 ligand exhibits antidepressant-like activity in preclinical tests. Neuroscience Letters. 405(1-2):111-5.

• Kinney JW, Davis CN, Tabarean I, Conti B, Bartfai T, Behrens MM (2006). A specific role for NR2A-containing NMDA receptors in the maintenance of parvalbumin and GAD67 immunoreactivity in cultured interneurons. Journal of Neuroscience. 26(5):1604-15.

• Shi TJ, Hua XY, Lu X, Malkmus S, Kinney J, Holmberg K, Wirz S, Ceccatelli S, Yaksh T, Bartfai T, Hokfelt T (2006). Sensory neuronal phenotype in galanin receptor 2 knockout mice: focus on dorsal root ganglion neurone development and pain behavior. European Journal of Neuroscience. 23(3):627-36.

• Rustay NR, Wrenn CC, Kinney JW, Holmes A, Bailey KR, Sullivan TL, Harris AP, Long KC, Saavedra MC, Starosta G, Innerfield CE, Yang RJ, Dreiling JL, Crawley JN (2005). Galanin impairs performance on learning and memory tasks: findings from galanin transgenic and GAL-R1 knockout mice. Neuropeptides. 39(3):239-43.

• Lu X, Barr AM, Kinney JW, Sanna P, Conti B, Behrens MM, Bartfai T (2005). A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus. Proceedings of the National Academy of Sciences of the United States of America. 102(3):874-9.

• Wrenn CC, Kinney JW, Marriott LK, Holmes A, Harris AP, Saavedra MC, Starosta G, Innerfield CE, Jacoby AS, Shine J, Iismaa TP, Wenk GL, Crawley JN (2004). Learning and memory performance in mice lacking the GAL-R1 subtype of galanin receptor. European Journal of Neuroscience. 19(5):1384-96.

• Kinney JW, Starosta G, Crawley JN (2003). Central galanin administration blocks consolidation of spatial learning. Neurobiology of Learning and Memory. 80(1):42-54.

• Holmes A, Kinney JW, Wrenn CC, Li Q, Yang RJ, Ma L, Vishwanath J, Saavedra MC, Innerfield CE, Jacoby AS, Shine J, Iismaa TP, Crawley JN (2003). Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze. Neuropsychopharmacology. 28(6):1031-44.

• Wrenn CC, Marriott LK, Kinney JW, Holmes A, Wenk GL, Crawley JN (2002). Galanin peptide levels in hippocampus and cortex of galanin-overexpressing transgenic mice evaluated for cognitive performance. Neuropeptides. 36(6):413-26.

• Kinney JW, Starosta G, Holmes A, Wrenn CC, Yang RJ, Harris AP, Long KC, Crawley JN (2002). Deficits in trace cued fear conditioning in galanin-treated rats and galanin-overexpressing transgenic mice. Learning & Memory. 9(4):178-90.

• Kinney JW, Scruggs B, Avery DD (2001). Peripheral administration of urocortin suppresses operant responding for food reward. Peptides. 22(4):583-7.